The challenge of breath analysis for clinical diagnosis and therapeutic monitoring

被引：110

作者：

Smith, David

Spanel, Patrik

机构：

[1] Keele Univ, Sch Med, Ctr Sci & Technol Med, Stoke On Trent ST4 7QB, Staffs, England

[2] Acad Sci Czech Republic, J Heyrovsky Inst Phys Chem, CR-18223 Prague 8, Czech Republic

来源：

ANALYST | 2007年 / 132卷 / 05期

关键词：

D O I：

10.1039/b700542n

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The potential of breath analysis for clinical diagnosis and the strengths and weaknesses of the analytical methods used are discussed. Special attention is given to selected ion flow tube mass spectrometry, SIFT-MS, using which on-line real-time analyses of single breath exhalations can be carried out. Illustrative data on the concentration distributions of several breath metabolites amongst the healthy population are presented and their relations to disease when elevated above the normal are alluded to.

引用

收藏

页码：390 / 396

页数：7

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