Host factors exploited by retroviruses

被引：206

作者：

Goff, Stephen P.

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Biochem & Mol Biophys, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Dept Microbiol, Howard Hughes Med Inst, New York, NY 10032 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2007年 / 5卷 / 04期

关键词：

D O I：

10.1038/nrmicro1541

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Retroviruses make a long and complex journey from outside the cell to the nucleus in the early stages of infection, and then an equally long journey back out again in the late stages of infection. Ongoing efforts are identifying an enormous array of cellular proteins that are used by the viruses in the course of their travels. These host factors are potential new targets for therapeutic intervention.

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页码：253 / 263

页数：11

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