Marine actinomycetes as a source of novel secondary metabolites

被引:195
作者
Fiedler, HP
Bruntner, C
Bull, AT
Ward, AC
Goodfellow, M
Potterat, O
Puder, C
Mihm, G
机构
[1] Univ Tubingen, Inst Mikrobiol, D-72076 Tubingen, Germany
[2] Univ Kent, Res Sch Biosci, Canterbury CT2 7NJ, Kent, England
[3] Newcastle Univ, Sch Biol, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
[4] Boehringer Ingelheim Pharma GmbH & Co KG, D-88397 Biberach, Germany
来源
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY | 2005年 / 87卷 / 01期
基金
英国自然环境研究理事会;
关键词
actinomycetes; antibiotics; marine natural products;
D O I
10.1007/s10482-004-6538-8
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be producers of well known chemically diverse antibiotics isolated from terrestrial streptomycetes, as in the case of marine Micromonospora strains. New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032.
引用
收藏
页码:37 / 42
页数:6
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