The development of bioartificial nerve grafts for peripheral-nerve regeneration

被引：200

作者：

Heath, CA ^{[1
]}

Rutkowski, GE ^{[1
]}

机构：

[1] Iowa State Univ, Dept Chem Engn, Ames, IA 50011 USA

来源：

TRENDS IN BIOTECHNOLOGY | 1998年 / 16卷 / 04期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0167-7799(97)01165-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

This article describes recent, significant scientific advances leading to the development of the bioartificial nerve graft. Schwann cells, which play an active role in the repair and function of peripheral nerves, are used to seed a synthetic, often resorbable conduit, which is then used to bridge and repair nerve gaps caused by injury or disease. By enhancing the rate and extent of regeneration, the bioartificial nerve graft holds great promise for improving recovery in the peripheral (and central) nervous system.

引用

页码：163 / 168

页数：6

共 46 条

[1] BLIND-ENDED SEMIPERMEABLE GUIDANCE CHANNELS SUPPORT PERIPHERAL-NERVE REGENERATION IN THE ABSENCE OF A DISTAL NERVE STUMP [J].