ANTIVIRAL COMPOUNDS IN THE PIPELINE TO TACKLE H1N1 INFLUENZA INFECTION

被引:6
作者
Beigel, J. H. [1 ]
机构
[1] NCI, Immunoregulat Lab, Div Intramural Res, NIAID,SAIC Frederick Inc,NIH, Frederick, MD 21702 USA
基金
美国国家卫生研究院;
关键词
CYCLOPENTANE NEURAMINIDASE INHIBITORS; IN-VIVO ACTIVITIES; A VIRUS-INFECTION; H5N1; VIRUS; PASSIVE IMMUNOTHERAPY; CELL-CULTURE; OSELTAMIVIR; EFFICACY; COMBINATION; ZANAMIVIR;
D O I
10.1358/dof.2010.035.05.1487081
中图分类号
R9 [药学];
学科分类号
100702 [药剂学];
摘要
The recent pandemic of H1N1 has demonstrated the potential vulnerability of the human population to novel influenza viruses. While there is recent increased interest and effort in developing effective anti-influenza agents, few new products have entered clinical studies. This review will highlight the limited armamentarium of licensed influenza agents, and discuss novel compounds and strategies that have entered clinical studies and may therefore be imminently available to the treating clinician.
引用
收藏
页码:385 / 392
页数:8
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