The Human Phenome Project

被引：273

作者：

Freimer, N

Sabatti, C

机构：

[1] Ctr Neurobehav Genet, Inst Neuropsychiat, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Inst Brain Res, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Dept Human Genet, Los Angeles, CA 90095 USA

[4] Univ Calif Los Angeles, Dept Stat, Los Angeles, CA 90095 USA

来源：

NATURE GENETICS | 2003年 / 34卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/ng0503-15

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A principal goal of genetic research is to identify specific genotypes that are associated with human phenotypes. it will soon be possible to conduct genome-wide genotyping on a massive scale. Our current approaches for defining and assaying phenotypes may be inadequate for making optimal use of such genotypic data. We propose an international effort to create phenomic databases, that is, comprehensive assemblages of systematically collected phenotypic information, and to develop new approaches for analyzing such phenotypic data. We term this effort the Human Phenome Project and suggest a scientific and organizational scope for the project.

引用

页码：15 / 21

页数：7