Catalase activity in human erythrocytes: Effect of phenoxyherbicides and their metabolites

被引：46

作者：

Bukowska, B ^{[1
]}

Chajdys, A ^{[1
]}

Duda, W ^{[1
]}

Duchnowiz, P ^{[1
]}

机构：

[1] Univ Lodz, Dept Biophys & Environm Pollut, PL-90237 Lodz, Poland

来源：

CELL BIOLOGY INTERNATIONAL | 2000年 / 24卷 / 10期

关键词：

catalase; 2,4-dichlorophenoxyacetic acid (2,4-D); 4-chloro-2-methylphenoxyacetic acid (MCPA); 2,4-dichlorophenol (2,4-DCP); 2,4,5-trichlorophenol (2,4,5-TCP); 2,4-dimethylphenol (2,4-DMP);

D O I：

10.1006/cbir.2000.0553

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1.6-hydrogen peroxide: hydro gen peroxide oxidoreductase). 4-chloro-2-methylphenoxyacetic acid (MCPA), 2,4-dimethylphenol (2,4-DMP) and 2,4-dichlorophenoxyacetic acid (2,4-D) did not affect CAT activity, but 2,4-dichlorophenol (2,4-DCP) and 2,4,5-trichlorophenol (2,4,5-TCP) decrease its activity, the latter being the more inhibitory. (C) 2000 Academic Press.

引用

页码：705 / 711

页数：7

共 23 条

[1]

ADAM DKM, 1996, S AFR J SCI, V92, P426

[2]

AEBI H, 1984, METHOD ENZYMOL, V105, P121

[3]

Bukowska B, 1998, BIOCHEM MOL BIOL INT, V45, P47

[4]

BUSLOVICH SY, 1982, GIG SANIT, V10, P76

[5] DEGRADATION OF 2,4-DICHLOROPHENOXYACETIC ACID BY PSEUDOMONAS-CEPACIA DBO1(PRO101) IN A DUAL-SUBSTRATE CHEMOSTAT [J].

DAUGHERTY, DD ;

KAREL, SF .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1994, 60 (09) :3261-3267

[6] CATALASE - PHYSICAL AND CHEMICAL PROPERTIES, MECHANISM OF CATALYSIS, AND PHYSIOLOGICAL ROLE [J].

DEISSEROTH, A ;

DOUNCE, AL .

PHYSIOLOGICAL REVIEWS, 1970, 50 (03) :319-+

[7]

DRABKIN DL, 1946, J BIOL CHEM, V164, P703

[8] THE MULTIPLE FUNCTIONS OF HEMOGLOBIN [J].

GIARDINA, B ;

MESSANA, I ;

SCATENA, R ;

CASTAGNOLA, M .

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1995, 30 (03) :165-196

[9]

Juteau P, 1995, APPL MICROBIOL BIOT, V44, P218, DOI 10.1007/BF00164505

[10] THE BIOTRANSFORMATION OF 3 C-14-LABELED PHENOLIC-COMPOUNDS IN 12 SPECIES OF FRESH-WATER FISH [J].

LAYIWOLA, PJ ;

LINNECAR, DFC ;

KNIGHTS, B .

XENOBIOTICA, 1983, 13 (02) :107-113

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