Antiangiogenic therapy for primary and metastatic brain tumors

被引：18

作者：

Purow, B ^{[1
]}

Fine, HA ^{[1
]}

机构：

[1] NINDS, Neuro Oncol Branch, NCI, NIH, Bethesda, MD 20892 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2004年 / 18卷 / 05期

关键词：

D O I：

10.1016/j.hoc.2004.05.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We first provide the theoretic foundation of antiangiogenic therapy by describing the biology of angiogenesis as it applies to brain tumors. We then outline experimental antiangiogenic therapies that are being applied preclinically to brain tumors, as well as published clinical trial data and ongoing clinical trials in patients. Primary and metastatic brain tumors are covered, although there is far less exploration in the literature of brain metastases.

引用

页码：1161 / +

页数：22

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