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The role of host immune responses in determining the outcome of HIV infection

被引：48
作者：
Westby, M
Manca, F
Dalgleish, AG
机构：
[1] UNIV GENOA, SAN MARTINO HOSP, DEPT IMMUNOL, I-16132 GENOA, ITALY
[2] ADV BIOTECHNOL CTR, I-16132 GENOA, ITALY
来源：
IMMUNOLOGY TODAY | 1996年 / 17卷 / 03期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/0167-5699(96)80603-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The progression of disease following infection with human immunodeficiency virus (HIV) correlates with an activated immune system and would appear to depend to some degree on the immunogenetics of the host. Here, Michael Westby, Fabrizio Manca and Angus Dalgleish discuss the evidence for HLA determination of clinical outcome and the potential implications of a restricted T-cell receptor repertoire for pathogenesis.
引用
收藏
页码：120 / 126
页数：7
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