DNA repair: Caretakers of the genome?

被引：54

作者：

Cunningham, RP

机构：

来源：

CURRENT BIOLOGY | 1997年 / 7卷 / 09期

关键词：

D O I：

10.1016/S0960-9822(06)00286-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent results show that tale 8-oxoguanine DNA repair system is functionally conserved in bacteria and mammals. The bacterial system protects the genome from the mutagenic effects of oxidative stress; the role of the mammalian system is expected to be similar and defects in it may increase susceptibility to cancer.

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页码：R576 / R579

页数：4

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