Highly efficient reduction of unactivated aryl and alkyl iodides by a ground-state neutral organic electron donor

被引：128

作者：

Murphy, JA ^{[1
]}

Khan, TA ^{[1
]}

Zhou, SZ ^{[1
]}

Thomson, DW ^{[1
]}

Mahesh, M ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 09期

基金：

英国工程与自然科学研究理事会;

关键词：

cyclization; electron transfer; radical reactions; reduction; synthetic methods;

D O I：

10.1002/anie.200462038

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electron-transfer reductions of unactivated aryl and alkyl iodides with a neutral ground-state organic molecule are reported. The reducing agent 1 is formed in two steps from N-methylbenzimidazole using very simple chemistry, and subsequent treatment of the iodoalkane or-arene with 1 affords cyclized products (see scheme). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1356 / 1360

页数：5

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