Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

被引：10

作者：

Albada, H. Bauke ^{[1
,2
]}

de Vries, Jan Willem ^{[3
]}

Liu, Qing ^{[3
]}

Golub, Eyal ^{[1
]}

Klement, Niels ^{[3
]}

Herrmann, Andreas ^{[3
]}

Willner, Itamar ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Inst Chem, Minerva Ctr Biohybrid Complex Syst, IL-91904 Jerusalem, Israel

[2] Wageningen Univ, Organ Chem Lab, NL-6700 AP Wageningen, Netherlands

[3] Univ Groningen, Zernike Inst Adv Mat, Groningen, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 32期

基金：

以色列科学基金会;

关键词：

QUADRUPLEX-CONTROLLED AGGREGATION; PEROXIDASE-MIMICKING DNAZYME; DNA NANOSTRUCTURES; NUCLEIC-ACIDS; NANOPARTICLES; APTASENSORS; TELOMERASE; COMPLEXES; OXIDASE; SENSORS;

D O I：

10.1039/c6cc01115b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Lipidated DNAzymes or a lipidated Cu(II)-complex and lipidated aptamer sequences form supramolecular assemblies of micellar nucleoapzymes for the enhanced oxidation of dopamine to aminochrome. The catalytic functions of the micellar nucleoapzymes are attributed to the concentration of the substrate, using the aptamer units, in close proximity to the active sites.

引用

页码：5561 / 5564

页数：4

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