The facile preparation of alkenyl metathesis synthons

被引：101

作者：

Baughman, TW ^{[1
]}

Sworen, JC ^{[1
]}

Wagener, KB ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, George & Josephine Butler Polymer Res Lab, Gainesville, FL 32605 USA

来源：

TETRAHEDRON | 2004年 / 60卷 / 48期

基金：

美国国家科学基金会; 美国国家航空航天局;

关键词：

alpha-olefin; cross-metathesis; alkenyl halide; ADMET; metathesis;

D O I：

10.1016/j.tet.2004.09.021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report synthetic methodology allowing the preparation of any length alkenyl halide from inexpensive starting reagents. Standard organic transformations were used to prepare straight chain alpha-olefin halides in excellent overall yields with no detectable olefin isomerization and full recovery of any unreacted starting material. Reported transformations can be used for the selective incorporation of pure a-olefin metathesis sites in highly functionalized molecules. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：10943 / 10948

页数：6

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