Mitral Valve Surgery in Advanced Heart Failure

被引：102

作者：

Di Salvo, Thomas G. ^{[1
]}

Acker, Michael A. ^{[2
]}

Dec, G. William ^{[3
]}

Byrne, John G. ^{[1
]}

机构：

[1] Vanderbilt Univ, Nashville, TN USA

[2] Univ Penn, Philadelphia, PA 19104 USA

[3] Massachusetts Gen Hosp, Boston, MA 02114 USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2010年 / 55卷 / 04期

关键词：

mitral regurgitation; heart failure; cardiac surgery; CARDIAC RESYNCHRONIZATION THERAPY; LEFT-VENTRICULAR FUNCTION; COLLEGE-OF-CARDIOLOGY; LONG-TERM SURVIVAL; DILATED CARDIOMYOPATHY; AFTERLOAD REDUCTION; SURGICAL-TREATMENT; SUPPORT DEVICE; REGURGITATION; REPAIR;

D O I：

10.1016/j.jacc.2009.08.059

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The appropriateness and timing of mitral valve surgery in patients with advanced heart failure and severe mitral regurgitation remains controversial. Recent surgical results provide evidence for beneficial effects on left ventricular remodeling and functional capacity. Given the absence of randomized trials comparing the outcomes of mitral valve surgery to medical therapy, however, clinical decision making regarding surgery for these fragile patients poses a dilemma to thoughtful clinicians. This paper reviews the pathophysiology of mitral regurgitation in heart failure and proposes an integrated approach to management. (J Am Coll Cardiol 2010; 55: 271-82) (C) 2010 by the American College of Cardiology Foundation

引用

收藏

页码：271 / 282

页数：12

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