Oxytetracycline as environmental contaminant in arable lands

被引：37

作者：

Brambilla, Gianfranco ^{[1
]}

Patrizii, Michele

De Filippis, Stefania Paola

Bonazzi, Giuseppe

Mantovi, Paolo

Barchi, Davide

Migliore, Luciana

机构：

[1] ISS, Dept Environm, Rome, Italy

[2] Univ Roma Tor Vergata, Dept Biol, Rome, Italy

[3] CRPA, Reggio Emilia, Italy

[4] Reg Emilia Romagna, Bologna, Italy

来源：

ANALYTICA CHIMICA ACTA | 2007年 / 586卷 / 1-2期

关键词：

oxytetracycline; manure contamination; soil contamination;

D O I：

10.1016/j.aca.2006.11.019

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Oxytetracycline (OXY) is a broad-range antimicrobial routinely used in pig production, at doses in the range of few g/kg of medicated feed, during the weaning period. It could persist at ppm level in pig liquid manure that routinely is used for organic fertilisation. In the present work we describe a methodology to study OXY environmental fate in arable land where crops are cultivated for animal feeding purposes. A liquid-liquid extraction followed by metal chelate affinity chromatography was applied to environmental samples of manures and soils drawn within a case-control study. Extracts were then analysed by high performance liquid chromatography with UV/DAD detection., using a reverse phase column, and expressing the results as 4-epioxytetracycline epimer. Results indicate OXY is well retained at mg kg(-1) levels in soil exposed to contaminated pig manure fertilisation. Such compartment could constitute an abiotic reservoir for the systemic and/or for the external contamination of corn. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：326 / 329

页数：4

共 20 条

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