Gene admixture in the Silk Road region of China:: Evidence from mtDNA and melanocortin 1 receptor polymorphism

被引：70

作者：

Yao, YG

Lü, XM

Luo, HR

Li, WH

Zhang, YP ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Zool, Lab Cellular & Mol Evolut, Kunming 650223, Peoples R China

[2] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

来源：

GENES & GENETIC SYSTEMS | 2000年 / 75卷 / 04期

关键词：

D O I：

10.1266/ggs.75.173

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mitochondrial DNA control region segment I sequences and melanocortin 1 receptor (MC1R) gene polymorphism were examined in ethnic populations in the silk road region of China. Both the frequencies of the MC1R variants and the results of mtDNA data in this region presented intermediate values between those of Europe and East and Southeast Asia, which suggested extensive gene admixture in this area and was in general agreement with previous studies. Phylogenetic analysis of the ethnic populations in the Silk Road region that based on mtDNA data didn't show expected cluster pattern according to their ethnogenesis. We suspect that a high migration rate in female among these closely related populations and other three demographic events might account for it.

引用

页码：173 / 178

页数：6

共 22 条

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