Commercialization of animal biotechnology

被引:45
作者
Faber, DC [1 ]
Molina, JA [1 ]
Ohlrichs, CL [1 ]
Vander Zwaag, DF [1 ]
Ferré, LB [1 ]
机构
[1] Trans Ova Genet, Sioux Ctr, IA 51250 USA
关键词
commercialization; in vitro fertilization; sexing; cloning; transgenics;
D O I
10.1016/S0093-691X(02)01264-5
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Commercialization of animal biotechnology is a wide-ranging topic for discussion. In this paper, we will attempt to review embryo transfer (ET) and related technologies that relate to food-producing mammals. A brief review of the history of advances in biotechnology will provide a glimpse to present and future applications. Commercialization of animal biotechnology is presently taking two pathways. The first application involves the use of animals for biomedical purposes. Very few companies have developed all of the core competencies and intellectual properties to complete the bridge from lab bench to product. The second pathway of application is for the production of animals used for food. Artificial insemination (AI), embryo transfer, in vitro fertilization (IVF), cloning, transgenics, and genomics all are components of the toolbox for present and future applications. Individually, these are powerful tools capable of providing significant improvements in productivity. Combinations of these technologies coupled with information systems and data analysis, will provide even more significant change in the next decade. Any strategies for the commercial application of animal biotechnology must include a careful review of regulatory and social concerns. Careful review of industry infrastructure is also important. Our colleagues in plant biotechnology have helped highlight some of these pitfalls and provide us with a retrospective review. In summary, today we have core competencies that provide a wealth of opportunities for the members of this society, commercial companies, producers, and the general population. Successful commercialization will benefit all of the above stakeholders. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:125 / 138
页数:14
相关论文
共 98 条
[1]   Production of goats by somatic cell nuclear transfer [J].
Baguisi, A ;
Behboodi, E ;
Melican, DT ;
Pollock, JS ;
Destrempes, MM ;
Cammuso, C ;
Williams, JL ;
Nims, SD ;
Porter, CA ;
Midura, P ;
Palacios, MJ ;
Ayres, SL ;
Denniston, RS ;
Hayes, ML ;
Ziomek, CA ;
Meade, HM ;
Godke, RA ;
Gavin, WG ;
Overström, EW ;
Echelard, Y .
NATURE BIOTECHNOLOGY, 1999, 17 (05) :456-461
[2]   BIRTH OF LARGE CALVES THAT DEVELOPED FROM IN VITRO-DERIVED BOVINE EMBRYOS [J].
BEHBOODI, E ;
ANDERSON, GB ;
BONDURANT, RH ;
CARGILL, SL ;
KREUSCHER, BR ;
MEDRANO, JF ;
MURRAY, JD .
THERIOGENOLOGY, 1995, 44 (02) :227-232
[3]   A new approach to immunological sexing of sperm [J].
Blecher, SR ;
Howie, R ;
Li, S ;
Detmar, J ;
Blahut, LM .
THERIOGENOLOGY, 1999, 52 (08) :1309-1321
[4]   Manipulation of follicular development to produce developmentally competent bovine cytes [J].
Blondin, P ;
Bousquet, D ;
Twagiramungu, H ;
Barnes, F ;
Sirard, MA .
BIOLOGY OF REPRODUCTION, 2002, 66 (01) :38-43
[5]  
BOLS PEJ, 1997, THESIS U GENT
[6]   In vitro embryo production in the cow: An effective alternative to the conventional embryo production approach [J].
Bousquet, D ;
Twagiramungu, H ;
Morin, N ;
Brisson, C ;
Carboneau, G ;
Durocher, J .
THERIOGENOLOGY, 1999, 51 (01) :59-70
[7]   NORMAL DEVELOPMENT FOLLOWING INVITRO FERTILIZATION IN THE COW [J].
BRACKETT, BG ;
BOUSQUET, D ;
BOICE, ML ;
DONAWICK, WJ ;
EVANS, JF ;
DRESSEL, MA .
BIOLOGY OF REPRODUCTION, 1982, 27 (01) :147-158
[8]   A REVIEW OF BOVINE FERTILIZATION INVITRO [J].
BRACKETT, BG .
THERIOGENOLOGY, 1983, 19 (01) :1-15
[9]   PCR-SEXING OF BOVINE EMBRYOS - A SIMPLIFIED PROTOCOL [J].
BREDBACKA, P ;
KANKAANPAA, A ;
PEIPPO, J .
THERIOGENOLOGY, 1995, 44 (02) :167-176
[10]   Developing efficient strategies for the generation of transgenic cattle which produce biopharmaceuticals in milk [J].
Brink, MF ;
Bishop, MD ;
Pieper, FR .
THERIOGENOLOGY, 2000, 53 (01) :139-148