A new regioselective synthesis and ambient light photochemistry of quinazolin-1-oxides

被引：21

作者：

Coskun, Necdet ^{[1
]}

Cetin, Meliha ^{[1
]}

机构：

[1] Uludag Univ, Dept Chem, TR-16059 Bursa, Turkey

来源：

TETRAHEDRON | 2007年 / 63卷 / 14期

关键词：

N-oxides; quinazoline; quinazolin-1-ol; quinazolin-1-oxide; qui nazolin-3-oxide; quinazolin-4(3H)-one; ambient light photochemistry; rearrangement; photochemical deoxygenation; solvent effect; solvent isotope effect;

D O I：

10.1016/j.tet.2007.02.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Quinazolin-1-oxides were prepared by the oxidation of tetrahydroquinazolines with H2O2-tungstate and their ambient light photochemistry was investigated. Substituent effects on their photochemical cyclization and the reactions of the products 1aH- [1,2]oxazireno[2,3-a]quinazolines under photochemical and thermal conditions are reported. The cyclization of quinazolin-1-oxides and the reactions of 1aH-[1,2]oxazireno[2,3-a]quinazolines show pronounced solvent isotope and solvent effects. (c) 2007 Published by Elsevier Ltd.

引用

页码：2966 / 2972

页数：7

共 20 条

[1] THE PHOTOCHEMISTRY OF THE N-OXIDE FUNCTION [J].