p53: 25 years of research and more questions to answer

被引:53
作者
Bourdon, JC
De Laurenzi, V
Melino, G
Lane, D [1 ]
机构
[1] Univ Dundee, Ninewells Hosp, Dept Surg & Mol Oncol, Dundee DD1 9SY, Scotland
[2] Univ Dundee, Med Sch, Canc Res UK, Cell Transformat Res Grp, Dundee DD1 9SY, Scotland
[3] Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, I-00133 Rome, Italy
[4] Univ Leicester, MRC Toxicol Unit, Leicester LE1 9HN, Leics, England
关键词
D O I
10.1038/sj.cdd.4401243
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:397 / 399
页数:3
相关论文
共 48 条
  • [1] DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    Bakkenist, CJ
    Kastan, MB
    [J]. NATURE, 2003, 421 (6922) : 499 - 506
  • [2] Enhanced phosphorylation of p53 by ATN in response to DNA damage
    Banin, S
    Moyal, L
    Shieh, SY
    Taya, Y
    Anderson, CW
    Chessa, L
    Smorodinsky, NI
    Prives, C
    Reiss, Y
    Shiloh, Y
    Ziv, Y
    [J]. SCIENCE, 1998, 281 (5383) : 1674 - 1677
  • [3] p53-dependent pathways of apoptosis
    Benchimol, S
    [J]. CELL DEATH AND DIFFERENTIATION, 2001, 8 (11) : 1049 - 1051
  • [4] iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
    Bergamaschi, D
    Samuels, Y
    O'Neil, NJ
    Trigiante, G
    Crook, T
    Hsieh, JK
    O'Connor, DJ
    Zhong, S
    Campargue, I
    Tomlinson, ML
    Kuwabara, PE
    Lu, X
    [J]. NATURE GENETICS, 2003, 33 (02) : 162 - 167
  • [5] Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane
    Bourdon, JC
    Renzing, J
    Robertson, PL
    Fernandes, KN
    Lane, DP
    [J]. JOURNAL OF CELL BIOLOGY, 2002, 158 (02) : 235 - 246
  • [6] Further characterisation of the p53 responsive element - Identification of new candidate genes for trans-activation by p53
    Bourdon, JC
    DeguinChambon, V
    Lelong, JC
    Dessen, P
    May, P
    Debuire, B
    May, E
    [J]. ONCOGENE, 1997, 14 (01) : 85 - 94
  • [7] Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
    Canman, CE
    Lim, DS
    Cimprich, KA
    Taya, Y
    Tamai, K
    Sakaguchi, K
    Appella, E
    Kastan, MB
    Siliciano, JD
    [J]. SCIENCE, 1998, 281 (5383) : 1677 - 1679
  • [8] Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe
    Castedo, M
    Perfettini, JL
    Roumier, T
    Kroemer, G
    [J]. CELL DEATH AND DIFFERENTIATION, 2002, 9 (12) : 1287 - 1293
  • [9] Apoptosis and the cell cycle: the p53 connection
    Choisy-Rossi, C
    Yonish-Rouach, E
    [J]. CELL DEATH AND DIFFERENTIATION, 1998, 5 (02) : 129 - 131
  • [10] Mouse models with modified p53 sequences to study cancer and ageing
    Clarke, AR
    Hollstein, M
    [J]. CELL DEATH AND DIFFERENTIATION, 2003, 10 (04) : 443 - 450