Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia

被引:35
作者
Nhiem, Nguyen Xuan [1 ,2 ]
Van Kiem, Phan [2 ]
Van Minh, Chau [2 ]
Ban, Ninh Khac [3 ]
Cuong, Nguyen Xuan [2 ]
Ha, Le Minh [2 ]
Tai, Bui Huu [1 ,2 ]
Quang, Iran Hong [1 ,2 ]
Tung, Nguyen Huu [1 ,2 ]
Kim, Young Ho [1 ]
机构
[1] Chungnam Natl Univ, Coll Pharm, Taejon 305764, South Korea
[2] Vietnam Acad Sci & Technol, Inst Nat Prod Chem, Hanoi, Vietnam
[3] VAST, Inst Ecol & Biol Resources, Hanoi, Vietnam
关键词
(1)H NMR; (13)C NMR; Momordica charantia; Cucurbitaceae; cucurbitane triterpene glycoside; momordicosides U-W; CONSTITUENTS;
D O I
10.1002/mrc.2582
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1-3). The structures of these compounds were determined to be (19R, 23R)-5 beta, 19-epoxy-19-methoxycucurbita-6,24-diene-3 beta, 23-diol 3-O-beta-D-allopyranoside (1), (23R)-5 beta, 19-epoxycucurbita-6,24-diene-3 beta, 23-diol 3-O-beta-D-allopyranoside (2), and (19R)-5 beta, 19-epoxy-19,25-dihydroxycucurbita-6,23(E)-diene-3 beta-ol 3-O-beta-D-glucopyranoside (3), by chemical and spectroscopic methods. Copyright (C) 2010 John Wiley & Sons, Ltd.
引用
收藏
页码:392 / 396
页数:5
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