The first total synthesis of trichostatin D

被引：48

作者：

Hosokawa, S ^{[1
]}

Ogura, T ^{[1
]}

Togashi, H ^{[1
]}

Tatsuta, K ^{[1
]}

机构：

[1] Waseda Univ, Dept Appl Chem, Sch Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 02期

关键词：

total synthesis; trichostatin D; vinylketene silyl N; O-acetal; glycosylation;

D O I：

10.1016/j.tetlet.2004.11.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Trichostatin D and 6-epi-trichostatin D have been stereoselectively svnthesized through a remote stereoinduction with a chiral vinylketene silyl N,O-acetal and glycosylation of hydroxymide under Mitsunobu conditions. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：333 / 337

页数：5

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