Highly stereoselective prins cyclization of (Z)- and (E)-γ-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

被引：73

作者：

Liu, Feng ^{[1
]}

Loh, Teck-Peng ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Math & Phys Sci, Div Chem & Biol Chem, Singapore 637616, Singapore

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 11期

关键词：

ACID PROMOTED CONDENSATION; CARBONYL-COMPOUNDS; SELECTIVE SYNTHESIS; NATURAL-PRODUCTS; TETRAHYDROFURAN; DIHYDROPYRANS; ALLYLSILANES; DIBROMIDES; ALDEHYDES; CONCISE;

D O I：

10.1021/ol070506n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method has been developed to construct 2,6-cis-4,5-dibromo-tetrasubstituted tetrahydropyran ( THP) rings with well-controlled stereochemistry in moderate to high yields.

引用

页码：2063 / 2066

页数：4

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