Erythromycin and clindamycin resistance and telithromycin susceptibility in Streptococcus agalactiae

被引:59
作者
Betriu, C [1 ]
Culebras, E [1 ]
Gómez, M [1 ]
Rodríguez-Avial, I [1 ]
Sánchez, BA [1 ]
Agreda, MC [1 ]
Picazo, JJ [1 ]
机构
[1] Hosp Clin San Carlos, Dept Clin Microbiol, Madrid 28040, Spain
关键词
D O I
10.1128/AAC.47.3.1112-1114.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The rates of resistance to erythromycin and clindamycin among Streptococcus agalactiae strains isolated in our hospital increased from 4.2 and 0.8% in 1993 to 17.4 and 12.1%, respectively, in 2001. Erythromycin resistance was mainly due to the presence of an Erm(B) methylase, while the M phenotype was detected in 3.8% of the strains. Telithromycin was very active against erythromycin-resistant strains, irrespective of their mechanisms of macrolide resistance.
引用
收藏
页码:1112 / 1114
页数:3
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