Too much hype, not enough hope: Are balanced reporting and proper controls too much to expect from therapeutic studies in animal models of neuromuscular diseases that presage clinical trials in humans?

被引:4
作者
Bretag, Allan [1 ]
机构
[1] Univ S Australia, Sansom Inst, Adelaide, SA 5001, Australia
关键词
D O I
10.1016/j.nmd.2007.02.001
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:203 / 205
页数:3
相关论文
共 19 条
[1]   Nitric oxide release combined with nonsteroidal anti inflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy [J].
Brunelli, Silvia ;
Sciorati, Clara ;
D'Antona, Giuseppe ;
Innocenzi, Anna ;
Covarello, Diego ;
Galvez, Beatriz G. ;
Perrotta, Cristiana ;
Monopoli, Angela ;
Sanvito, Francesca ;
Bottinelli, Roberto ;
Ongini, Ennio ;
Cossu, Giulio ;
Clementi, Emilio .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (01) :264-269
[2]   Treating muscular dystrophy with stem cells? [J].
Davies, Kay E. ;
Grounds, Miranda D. .
CELL, 2006, 127 (07) :1304-1306
[3]   Skeletal myogenic progenitors originating from embryonic dorsal aorta coexpress endothelial and myogenic markers and contribute to postnatal muscle growth and regeneration [J].
De Angelis, L ;
Berghella, L ;
Coletta, M ;
Lattanzi, L ;
Zanchi, M ;
Cusella-De Angelis, MG ;
Ponzetto, C ;
Cossu, G .
JOURNAL OF CELL BIOLOGY, 1999, 147 (04) :869-877
[4]   Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs [J].
Dell'Agnola, C ;
Wang, ZJ ;
Storb, R ;
Tapscott, SJ ;
Kuhr, CS ;
Hauschka, SD ;
Lee, RS ;
Sale, GE ;
Zellmer, E ;
Gisburne, S ;
Bogan, J ;
Kornegay, JN ;
Cooper, BJ ;
Gooley, TA ;
Little, MT .
BLOOD, 2004, 104 (13) :4311-4318
[5]   Therapeutic efforts in Duchenne muscular dystrophy; the need for a common language between basic scientists and clinicians [J].
Dubowitz, V .
NEUROMUSCULAR DISORDERS, 2004, 14 (8-9) :451-455
[6]   Therapeutic possibilities in muscular dystrophy: the hope versus the hype [J].
Dubowitz, V .
NEUROMUSCULAR DISORDERS, 2002, 12 (02) :113-116
[7]   Progressive muscular dystrophy in α-sarcoglycan-deficient mice [J].
Duclos, F ;
Straub, V ;
Moore, SA ;
Venzke, DP ;
Hrstka, RF ;
Crosbie, RH ;
Durbeej, M ;
Lebakken, CS ;
Ettinger, AJ ;
van der Meulen, J ;
Holt, KH ;
Lim, LE ;
Sanes, JR ;
Davidson, BL ;
Faulkner, JA ;
Williamson, R ;
Campbell, KP .
JOURNAL OF CELL BIOLOGY, 1998, 142 (06) :1461-1471
[8]   Phenotypic correction of α-sarcoglycan deficiency by intra-arterial injection of a muscle-specific serotype 1 rAAV vector [J].
Fougerousse, Francoise ;
Bartoli, Marc ;
Poupiot, Jerome ;
Arandel, Ludovic ;
Durand, Muriel ;
Guerchet, Nicolas ;
Gicquel, Evelyne ;
Danos, Olivier ;
Richard, Isabelle .
MOLECULAR THERAPY, 2007, 15 (01) :53-61
[9]  
Galvez BG, 2006, J CELL BIOL, V174, P231, DOI 10.1083/jcb.200512085
[10]   The allure of stem cell therapy for muscular dystrophy [J].
Grounds, Miranda D. ;
Davies, Kay E. .
NEUROMUSCULAR DISORDERS, 2007, 17 (03) :206-208