Resolution of (+/-)-ibuprofen using L-arginine-impregnated thin-layer chromatography

被引：48

作者：

Bhushan, R

Parshad, V

机构：

[1] Department of Chemistry, University of Roorkee

来源：

JOURNAL OF CHROMATOGRAPHY A | 1996年 / 721卷 / 02期

关键词：

D O I：

10.1016/0021-9673(95)00772-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The resolution of(+/-)-ibuprofen into its enantiomers was achieved by TLC on silica gel plates impregnated with optically pure L-arginine (0.5%), as the chiral selector, using acetonitrile-methanol-water (5:1:1, v/v/v) as the solvent system. The detection limit was 0.1 mu g.

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页码：369 / 372

页数：4

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