Synthesis of (±)-2′,3′-dideoxy-3′-fluoroapiosylpyrimide nucleosides

被引：11

作者：

Ahn, SK

Kim, D

Son, HJ

Jeong, BS

Hong, RK

Kim, BY

Kim, EN

Chung, KH

Kim, JW

机构：

[1] Seoul Natl Univ, Coll Pharm, Kwanak Gu, Seoul, South Korea

[2] Chong Kun Dang Res Inst, Guro Gu, Seoul, South Korea

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 09期

关键词：

D O I：

10.1039/a800665b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Various (+)-2',3'-dideoxy-3'-fluoroapiosylpyrimidine nucleoside analogs have been prepared.

引用

页码：967 / 968

页数：2

共 22 条

[1] SYNTHESIS OF (+/-)-2'-OXA-CARBOCYCLIC-2',3'-DIDEOXYNUCLEOSIDES AS POTENTIAL ANTI-HIV AGENTS [J].

BAMFORD, MJ ;

HUMBER, DC ;

STORER, R .

TETRAHEDRON LETTERS, 1991, 32 (02) :271-274

[2] SYNTHETIC STUDIES TOWARDS (-)-CARBA-3'-DEOXY-3'-FLUOROTHYMIDINE [J].

BERES, J ;

SAGI, G ;

BAITZGACS, E ;

TOMOSKOZI, I ;

GRUBER, L ;

OTVOS, L .

TETRAHEDRON, 1989, 45 (19) :6271-6280

[3] 4'-MODIFICATION OF CARBOCYCLIC NUCLEOSIDES - SYNTHESIS OF 4'-ALPHA-FLUORO, 4'-ALPHA-HYDROXY AND 4',6'-UNSATURATED DERIVATIVES OF THE ANTIVIRAL AGENT 2'-ARA-FLUORO CARBOCYCLIC GUANOSINE [J].

BIGGADIKE, K ;

BORTHWICK, AD .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (19) :1380-1382

[4]

CHAUDHARY SK, 1979, TETRAHEDRON LETT, P99

[5]

HAMMERSCHMIDT E, 1995, LIEBIGS ANN, P551

[6]

HAMMERSCHMIDT F, 1995, SYNTHESIS-STUTTGART, P415

[7] 4'-SUBSTITUTED NUCLEOSIDES .2. SYNTHESIS OF NUCLEOSIDE ANTIBIOTIC NUCLEOCIDIN [J].

JENKINS, ID ;

VERHEYDEN, JPH ;

MOFFATT, JG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (11) :3346-3357

[8]

LIPSHUTZ BH, 1992, SYNTHESIS-STUTTGART, P191

[9] AN ALLYLIC AZIDE ROUTE TO 4'-AZIDO CARBOCYCLIC NUCLEOSIDES - SYNTHESIS OF (+/-)-(1'ALPHA,2'ALPHA,3'BETA)- AND (+/-)-(1'ALPHA,2'BETA,3'BETA)-1-[1-AZIDO-2-HYDROXY-1-(HYDROXYMETHYL)-3-CYCLOPENTYL]THYMINE [J].

MAAG, H ;

RYDZEWSKI, RM .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (22) :5823-5831

[10] SYNTHESIS AND ANTI-HIV ACTIVITY OF 4'-AZIDO-METHOXYNUCLEOSIDES AND 4'-METHOXYNUCLEOSIDES [J].

MAAG, H ;

RYDZEWSKI, RM ;

MCROBERTS, MJ ;

CRAWFORDRUTH, D ;

VERHEYDEN, JPH ;

PRISBE, EJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (08) :1440-1451

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