The structure of mammalian fatty acid synthase turned back to front

被引：10

作者：

Cronan, JE

机构：

[1] Univ Illinois, Dept Microbiol, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Biochem, Urbana, IL 61801 USA

来源：

CHEMISTRY & BIOLOGY | 2004年 / 11卷 / 12期

关键词：

D O I：

10.1016/j.chembiol.2004.11.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

On page 1667 of this issue, Stuart Smith and colleagues [1] demonstrate that the animal fatty acid synthase is a head-to-head dimer rather than the head-to-tail dimer depicted in textbooks. This has important ramifications for the mechanisms of other multifunctional enzymes such as polyketide synthases [2].

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页码：1601 / 1602

页数：2

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