A new gene family (ariel) encodes asparagine-rich Entamoeba histolytica antigens, which resemble the amebic vaccine candidate serine-rich E-histolytica protein

被引：15

作者：

Mai, ZM ^{[1
]}

Samuelson, J ^{[1
]}

机构：

[1] Harvard Univ, Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA 02125 USA

来源：

INFECTION AND IMMUNITY | 1998年 / 66卷 / 01期

关键词：

D O I：

10.1128/IAI.66.1.353-355.1998

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A family of genes, called ariel; are named for and encode asparagine-rich Entamoeba histolytica antigens containing 2 to 16 octapeptide repeats. Ariel proteins, which are constitutively expressed by trophozoites, belong to a large antigen family that includes the serine-rich E. histolytica protein (SREHP), an amebic vaccine candidate.

引用

页码：353 / 355

页数：3

共 30 条

[1] MOLECULAR VARIATION IN PLASMODIUM-FALCIPARUM - POLYMORPHIC ANTIGENS OF ASEXUAL ERYTHROCYTIC STAGES [J].

ANDERS, RF ;

MCCOLL, DJ ;

COPPEL, RL .

ACTA TROPICA, 1993, 53 (3-4) :239-253

[2]

[Anonymous], 1988, Antibodies: A Laboratory Manual

[3] THE S-ANTIGEN OF PLASMODIUM-FALCIPARUM - REPERTOIRE AND ORIGIN OF DIVERSITY [J].

BICKLE, Q ;

ANDERS, RF ;

DAY, K ;

COPPEL, RL .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1993, 61 (02) :189-196

[4] DISCONTINUOUS TRANSCRIPTION AND ANTIGENIC VARIATION IN TRYPANOSOMES [J].

BORST, P .

ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :701-732

[5] ENTAMOEBA-HISTOLYTICA - A METHOD FOR ISOLATE IDENTIFICATION [J].

CLARK, CG ;

DIAMOND, LS .

EXPERIMENTAL PARASITOLOGY, 1993, 77 (04) :450-455

[6]

DELACRUZ VF, 1987, J BIOL CHEM, V262, P11935

[7] Cloning and expression of chitinases of Entamoebae [J].

delaVega, H ;

Specht, CA ;

Semino, CE ;

Robbins, PW ;

Eichinger, D ;

Caplivski, D ;

Ghosh, S ;

Samuelson, J .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1997, 85 (02) :139-147

[8] A REDESCRIPTION OF ENTAMOEBA-HISTOLYTICA SCHAUDINN, 1903 (EMENDED WALKER, 1911) SEPARATING IT FROM ENTAMOEBA-DISPAR BRUMPT, 1925 [J].

DIAMOND, LS ;

CLARK, CG .

JOURNAL OF EUKARYOTIC MICROBIOLOGY, 1993, 40 (03) :340-344

[9] RAPID PRODUCTION OF FULL-LENGTH CDNAS FROM RARE TRANSCRIPTS - AMPLIFICATION USING A SINGLE GENE-SPECIFIC OLIGONUCLEOTIDE PRIMER [J].

FROHMAN, MA ;

DUSH, MK ;

MARTIN, GR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) :8998-9002

[10] ANTIGENIC DIVERSITY AND THE TRANSMISSION DYNAMICS OF PLASMODIUM-FALCIPARUM [J].

GUPTA, S ;

TRENHOLME, K ;

ANDERSON, RM ;

DAY, KP .

SCIENCE, 1994, 263 (5149) :961-963

← 1 2 3 →