Chromatographic fingerprinting and related chemometric techniques for quality control of traditional Chinese medicines

被引:128
作者
Liang, Yizeng [1 ]
Xie, Peishan [2 ]
Chau, Footim [3 ]
机构
[1] Cent S Univ, Res Ctr Modernizat Chinese Med, Changsha 410083, Peoples R China
[2] Zhuhai Chromap Inst Herbal Med Res, Zhuhai, Peoples R China
[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China
关键词
Chemometric application; Quality control; Traditional Chinese medicines; Trends of chromatographic fingerprint development; PERFORMANCE LIQUID-CHROMATOGRAPHY; PERICARPIUM-CITRI-RETICULATAE; EVOLVING LATENT PROJECTIONS; 2-WAY MULTICOMPONENT DATA; WINDOW FACTOR-ANALYSIS; PRINCIPAL COMPONENT REGRESSION; TEA ANTIOXIDANT CAPACITY; MASS SPECTROMETRY DATA; GAS-CHROMATOGRAPHY; INFORMATION-THEORY;
D O I
10.1002/jssc.200900653
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Development of chromatographic fingerprint (CF) and related chemometric methods and their applications to quality control of traditional Chinese medicines (TCMs) were discussed CF is essentially a kind of quality control method for TCMs (or Chinese herbal medicines). Also, it is a quality-relevant-data high-throughput and integral tool to explore chemically the complexity of TCMs. With the help of chemometrics, some difficulties in evaluation and analysis of CFs, such as calculation of information content, peak alignment. pattern analysis, deconvolution of overlapping peaks, etc. could be well solved To further explore TCMs synergic quality, intensive study of CF coupled with chemometrics will create the possibility to achieve the aim to reveal the working mechanisms of TCMs and to further control and strengthen TCMs' intrinsic quality in a comprehensive manner
引用
收藏
页码:410 / 421
页数:12
相关论文
共 125 条
[1]   Feature detection and alignment of hyphenated chromatographic-mass spectrometric data -: Extraction of pure ion chromatograms using Kalman tracking [J].
Aberg, K. Magnus ;
Torgrip, Ralf J. O. ;
Kolmert, Johan ;
Schuppe-Koistinen, Ina ;
Lindberg, Johan .
JOURNAL OF CHROMATOGRAPHY A, 2008, 1192 (01) :139-146
[2]  
[Anonymous], 2000, CHIN TRADIT PAT MED, V22, P671
[3]  
ANTHONY ML, 1994, MOL PHARMACOL, V46, P199
[4]   Sensitive and selective ion chromatographic method for the determination of trace beryllium in water samples [J].
Bashir, W ;
Paull, B .
JOURNAL OF CHROMATOGRAPHY A, 2001, 910 (02) :301-309
[5]  
Bauer R, 1998, DRUG INF J, V32, P101, DOI 10.1177/009286159803200114
[6]   THEORY OF ANALYTICAL-CHEMISTRY [J].
BOOKSH, KS ;
KOWALSKI, BR .
ANALYTICAL CHEMISTRY, 1994, 66 (15) :A782-A791
[7]   Multivariate detection limits estimators [J].
Boque, R ;
Rius, FX .
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 1996, 32 (01) :11-23
[8]   New targets and screening approaches in antimicrobial drug discovery [J].
Brown, ED ;
Wright, GD .
CHEMICAL REVIEWS, 2005, 105 (02) :759-774
[9]   Chromatographic alignment by warping and dynamic programming as a pre-processing tool for PARAFAC modelling of liquid chromatography-mass spectrometry data [J].
Bylund, D ;
Danielsson, R ;
Malmquist, G ;
Markides, KE .
JOURNAL OF CHROMATOGRAPHY A, 2002, 961 (02) :237-244
[10]   Elimination of uninformative variables for multivariate calibration [J].
Centner, V ;
Massart, DL ;
deNoord, OE ;
deJong, S ;
Vandeginste, BM ;
Sterna, C .
ANALYTICAL CHEMISTRY, 1996, 68 (21) :3851-3858