Dengue

被引：980

作者：

Guzman, Maria G. ^{[1
]}

Harris, Eva ^{[2
]}

机构：

[1] Pedro Kour Trop Med Inst, Havana, Cuba

[2] Univ Calif Berkeley, Sch Publ Hlth, Div Infect Dis & Vaccinol, Berkeley, CA 94720 USA

来源：

LANCET | 2015年 / 385卷 / 9966期

关键词：

ANTIBODY-DEPENDENT ENHANCEMENT; ORIGINAL ANTIGENIC SIN; HEMORRHAGIC-FEVER; VIRUS-INFECTIONS; AEDES-AEGYPTI; VASCULAR LEAKAGE; PROTECTIVE EFFICACY; DENDRITIC CELLS; KAMPHAENG PHET; ADULT PATIENTS;

D O I：

10.1016/S0140-6736(14)60572-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dengue viruses have spread rapidly within countries and across regions in the past few decades, resulting in an increased frequency of epidemics and severe dengue disease, hyperendemicity of multiple dengue virus serotypes in many tropical countries, and autochthonous transmission in Europe and the USA. Today, dengue is regarded as the most prevalent and rapidly spreading mosquito-borne viral disease of human beings. Importantly, the past decade has also seen an upsurge in research on dengue virology, pathogenesis, and immunology and in development of antivirals, vaccines, and new vector-control strategies that can positively impact dengue control and prevention.

引用

收藏

页码：453 / 465

页数：13

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