Solid phase synthesis of aminoboronic acids: Potent inhibitors of the hepatitis C virus NS3 proteinase

被引：26

作者：

Dunsdon, RM ^{[1
]}

Greening, JR ^{[1
]}

Jones, PS ^{[1
]}

Jordan, S ^{[1
]}

Wilson, FX ^{[1
]}

机构：

[1] Roche Discovery Welwyn, Dept Med Chem, Welwyn Garden City AL7 3AY, Herts, England

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2000年 / 10卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(00)00284-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Use of a resin bound diol as a boronic acid protecting group has been developed to allow the parallel synthesis of potent inhibitors of the hepatitis C virus NS3 serine proteinase. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：1577 / 1579

页数：3

共 8 条

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