ATP-dependent chromatin remodeling complexes contain ATPases of the Swi/Snf superfamily and alter DNA accessibility of chromatin in an ATP-dependent manner. Recently characterized INO80 and SWR1 complexes belong to a subfamily of these chromatin remodelers and are characterized by a split ATPase domain in the core ATPase subunit and the presence of Rvb proteins. INO80 and SWR1 complexes are evolutionarily conserved from yeast to human and have been implicated in transcription regulation, as well as DNA repair. The individual components, assembly patterns, and molecular mechanisms of the INO80 class of chromatin remodeling complexes are discussed in this review. (C) 2007 Elsevier B.V. All rights reserved.
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Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
Kato, M
Sasaki, M
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Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
Sasaki, M
Mizuno, S
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Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
Mizuno, S
Harata, M
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Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
机构:
Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
Kato, M
Sasaki, M
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机构:
Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
Sasaki, M
Mizuno, S
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机构:
Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan
Mizuno, S
Harata, M
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h-index: 0
机构:
Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, JapanTohoku Univ, Grad Sch Agr Sci, Div Life Sci, Dept Mol & Cell Biol,Lab Mol Biol,Aoba Ku, Sendai, Miyagi 9818555, Japan