Efficient synthesis of (E)-3-trifluoromethyl-3-aryl(hetaryl)acroleins

被引：16

作者：

Baraznenok, IL ^{[1
]}

Nenajdenko, VG ^{[1
]}

Balenkova, ES ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119899, Russia

来源：

TETRAHEDRON | 1998年 / 54卷 / 1-2期

关键词：

D O I：

10.1016/S0040-4020(97)10263-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of 4-dimethylamino-1,1,1-trifluro-3-buten-2-one with triflic anhydride or POCl3 were investigated. The 4-dimethylamino-1,1,1-trifluoro-3-buten-2-one / triflic anhydride complex reacts with electron-rich aromatics to give the corresponding CF3 substituted 3-aryl- or 3-hetarylacroleins. Reaction proceeds highly stereoselectively, giving preferentially E-isomer of aldehydes. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：119 / 128

页数：10

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