Acne: Inflammation

被引：114

作者：

Farrar, MD ^{[1
]}

Ingham, E ^{[1
]}

机构：

[1] Univ Leeds, Div Microbiol, Sch Biochem & Mol Biol, Skin Res Ctr, Leeds LS2 9JT, W Yorkshire, England

来源：

CLINICS IN DERMATOLOGY | 2004年 / 22卷 / 05期

关键词：

D O I：

10.1016/j.clindermatol.2004.03.006

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

The inflammatory stage of acne vulgaris is usually of greatest concern to the patient. A number of morphologically different inflammatory lesions may form that can be painful and unsightly. In 30% of patients, such lesions lead to scarring. Inflammatory acne and acne scarring can have significant psychological effects on the patient, including depression, anxiety, and poor self-image. Although inflammatory acne has been well characterized clinically, the mechanisms by which inflammatory lesions arise are still poorly understood. The human skin commensal bacterium, Propionibacterium acnes, has long been associated with inflammatory acne. This organism has been implicated over and above all of the other cutaneous microflora in contributing to the inflammatory response characteristic of acne. However, its precise role in the disease and its interaction with the human immune system remain to be elucidated.

引用

页码：380 / 384

页数：5

共 40 条

[1]

The possible role of reactive oxygen species generated by neutrophils in mediating acne inflammation [J].