Cycloaddition of homochiral imidazolinium ylides: A route to optically active pyrroloimidazoles

被引：48

作者：

Jones, RCF

Howard, KJ

Snaith, JS

机构：

[1] Department of Chemistry, University of Nottingham, Nottingham NG7 2RD, University Park

[2] Chemistry Department, Open University, Walton Hall

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 10期

关键词：

D O I：

10.1016/0040-4039(96)00113-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of either enantiomer of 1-benzyl-4-phenyl-2-imidazoline from phenylglycine is described. 'One-pot' generation and enantioselective 1,3-dipolar cycloaddition of homochiral azomethine ylides prepared from these imidazolines with a range of alkene dipolarophiles affords optically active hexahydropyrroloimidazole adducts.

引用

页码：1707 / 1710

页数：4

共 9 条

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