Living spontaneous gradient copolymers of acrylic acid and styrene: one-pot synthesis of pH-responsive amphiphiles

被引：60

作者：

Harrisson, Simon ^{[1
]}

Ercole, Francesca ^{[1
]}

Muir, Benjamin W. ^{[1
]}

机构：

[1] CSIRO Mol & Hlth Technol, Clayton, Vic 3168, Australia

来源：

POLYMER CHEMISTRY | 2010年 / 1卷 / 03期

关键词：

CHAIN-TRANSFER RAFT; RADICAL COPOLYMERIZATION; MALEIC-ANHYDRIDE; BLOCK-COPOLYMERS; SEQUENCE DISTRIBUTION; POLYMER SYNTHESIS; POLYMERIZATIONS; MODEL;

D O I：

10.1039/b9py00301k

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

RAFT polymerization was used to prepare copolymers of acrylic acid (AA) and styrene (STY) with mole fractions of STY (F(STY)) ranging from 0.1 to 0.3 and targeted degrees of polymerization between 50 and 150. The high reactivity of AA-terminal radicals towards STY in this system (r(AA) = 0.082) resulted in the spontaneous formation of composition gradients, resulting in polymers with block-like structures comprising a STY-rich segment, a relatively short transitional segment, and a segment of AA homopolymer. Atomic force microscopy analysis of thin films of the copolymer revealed phase separated structures which developed after exposure to water. Dynamic light scattering measurements showed pH-responsive amphiphilicity that resulted in dissolved polymer at neutral and basic pH and self-assembly in weakly acidic solutions.

引用

页码：326 / 332

页数：7

共 34 条

[1] Gradient copolymers [J].

Beginn, Uwe .

COLLOID AND POLYMER SCIENCE, 2008, 286 (13) :1465-1474

[2] One-step formation of functionalized block copolymers [J].

Benoit, D ;

Hawker, CJ ;

Huang, EE ;

Lin, ZQ ;

Russell, TP .

MACROMOLECULES, 2000, 33 (05) :1505-1507

[3]

Brandrup J., 1999, POLYM HDB, V1

[4] Effect of comonomer composition on the controlled free-radical copolymerization of styrene and maleic anhydride by reversible addition-fragmentation chain transfer (RAFT) [J].

Chernikova, E ;

Terpugova, P ;

Bui, CO ;

Charleux, B .

POLYMER, 2003, 44 (15) :4101-4107

[5] Direct synthesis of controlled poly(styrene-co-acrylic acid)s of various compositions by nitroxide-mediated random copolymerization [J].

Couvreur, L ;

Charleux, B ;

Guerret, O ;

Magnet, S .

MACROMOLECULAR CHEMISTRY AND PHYSICS, 2003, 204 (17) :2055-2063

[6] First nitroxide-mediated controlled free-radical polymerization of acrylic acid [J].

Couvreur, L ;

Lefay, C ;

Belleney, J ;

Charleux, B ;

Guerret, O ;

Magnet, S .

MACROMOLECULES, 2003, 36 (22) :8260-8267

[7] Radical copolymerization of maleic anhydride and substituted styrenes by reversible addition-fragmentation chain transfer (RAFT) polymerization [J].

Davies, MC ;

Dawkins, JV ;

Hourston, DJ .

POLYMER, 2005, 46 (06) :1739-1753

[8]

De Brouwer H, 2000, J POLYM SCI POL CHEM, V38, P3596, DOI 10.1002/1099-0518(20001001)38:19<3596::AID-POLA150>3.0.CO

[9]

2-F

[10] Polymer vesicles [J].

Discher, DE ;

Eisenberg, A .

SCIENCE, 2002, 297 (5583) :967-973

← 1 2 3 4 →