Coeliac disease - a future for peptide therapy?

被引：7

作者：

Mowat, AM ^{[1
]}

机构：

[1] Univ Glasgow, Western Infirm, Dept Bacteriol & Immunol, Glasgow G11 6NT, Lanark, Scotland

来源：

LANCET | 2000年 / 356卷 / 9226期

关键词：

D O I：

10.1016/S0140-6736(00)02499-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：270 / 271

页数：2

共 19 条

[1] In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope [J].

Anderson, RP ;

Degano, P ;

Godkin, AJ ;

Jewell, DP ;

Hill, AVS .

NATURE MEDICINE, 2000, 6 (03) :337-342

[2] The intestinal T cell response to α-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase [J].

Arentz-Hansen, H ;

Körner, R ;

Molberg, O ;

Quarsten, H ;

Vader, W ;

Kooy, YMC ;

Lundin, KEA ;

Koning, F ;

Roepstorff, P ;

Sollid, LM ;

McAdam, SN .

JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (04) :603-612

[3] INVITRO (ORGAN-CULTURE) STUDIES OF THE TOXICITY OF SPECIFIC A-GLIADIN PEPTIDES IN CELIAC-DISEASE [J].

DERITIS, G ;

AURICCHIO, S ;

JONES, HW ;

LEW, EJL ;

BERNARDIN, JE ;

KASARDA, DD .

GASTROENTEROLOGY, 1988, 94 (01) :41-49

[4] T-CELLS RECOGNIZE A PEPTIDE DERIVED FROM ALPHA-GLIADIN PRESENTED BY THE CELIAC DISEASE-ASSOCIATED HLA-DQ (ALPHA-1-ASTERISK-O5O1, BETA-1-ASTERISK-0201) HETERODIMER [J].

GJERTSEN, HA ;

LUNDIN, KEA ;

SOLLID, LM ;

ERIKSEN, JA ;

THORSBY, E .

HUMAN IMMUNOLOGY, 1994, 39 (04) :243-252

[5]

Lock C, 1991, Semin Immunol, V3, P247

[6] T cells orchestrate intestinal mucosal shape and integrity [J].

MacDonald, TT ;

Bajaj-Elliott, M ;

Pender, SLF .

IMMUNOLOGY TODAY, 1999, 20 (11) :505-510

[7]

MADDEN DR, 1995, ANNU REV IMMUNOL, V13, P587, DOI 10.1146/annurev.iy.13.040195.003103

[8] INVIVO TOXICITY OF A SYNTHETIC DODECAPEPTIDE FROM A-GLIADIN IN PATIENTS WITH CELIAC-DISEASE [J].

MANTZARIS, G ;

JEWELL, DP .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1991, 26 (04) :392-398

[9] Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease [J].

Molberg, O ;

Mcadam, SN ;

Körner, R ;

Quarsten, H ;

Kristiansen, C ;

Madsen, L ;

Fugger, L ;

Scott, H ;

Norén, O ;

Roepstorff, P ;

Lundin, KEA ;

Sjöström, H ;

Sollid, LM .

NATURE MEDICINE, 1998, 4 (06) :713-717

[10]

Mowat A, 1999, MUCOSAL IMMUNOLOGY, P587

← 1 2 →