D-Glucose as a pentavalent chiral scaffold

被引：35

作者：

Opatz, T

Kallus, C

Wunberg, T

Schmidt, W

Henke, S

Kunz, H

机构：

[1] Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany

[2] Aventis Pharma Deutschland GMBH, D-65926 Frankfurt, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 2003卷 / 08期

关键词：

combinatorial chemistry; solid-phase synthesis; carbohydrates; peptidomimetics;

D O I：

10.1002/ejoc.200390211

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel carbohydrate-based scaffold for combinatorial chemistry has been developed. This scaffold allows the selective attachment of five different side chains, giving rise to products of enormous structural diversity. As a demonstration of its usefulness, a series of model compounds has been prepared in high purity and yield by multistep parallel synthesis on a solid phase. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

引用

收藏

页码：1527 / 1536

页数：10

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