Activity of a peptide deformylase inhibitor LBM415 (NVP PDF-713) tested against recent clinical isolates from Japan

被引:5
作者
Bell, JM [1 ]
Turnidge, JD
Inoue, M
Kohno, S
Hirakata, Y
Ono, Y
Jones, RN
机构
[1] Womens & Childrens Hosp, Adelaide, SA, Australia
[2] Kitasato Univ, Sch Med, Kanagawa, Japan
[3] Nagasaki Univ, Sch Med, Nagasaki 852, Japan
[4] Teikyo Univ, Sch Med, Tokyo 173, Japan
[5] JONES Grp, JMI Labs, N Liberty, IA USA
关键词
in vitro activity; MDR; novel antimicrobial;
D O I
10.1093/jac/dkh547
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:276 / 278
页数:4
相关论文
共 11 条
[1]  
[Anonymous], 2003, NCCLS Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, V6th
[2]   Peptide deformylase as an antibacterial drug target:: Target validation and resistance development [J].
Apfel, CM ;
Locher, H ;
Evers, S ;
Takács, B ;
Hubschwerlen, C ;
Pirson, W ;
Page, MGP ;
Keck, W .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (04) :1058-1064
[3]   Antimicrobial resistance trends in community-acquired respiratory tract pathogens in the Western Pacific Region and South Africa: report from the SENTRY antimicrobial surveillance program, (1998-1999) including an in vitro evaluation of BMS284756 [J].
Bell, JM ;
Turnidge, JD ;
Jones, RN .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2002, 19 (02) :125-132
[4]   High prevalence of oxacillin-resistant Staphylococcus aureus isolates from hospitalized patients in Asia-Pacific and South Africa:: Results from SENTRY antimicrobial surveillance program, 1998-1999 [J].
Bell, JM ;
Turnidge, JD .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (03) :879-881
[5]   Antistaphylococcal activity of LBM415, a new peptide deformylase inhibitor, compared with those of other agents [J].
Credito, K ;
Lin, GR ;
Ednie, LM ;
Appelbaum, PC .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (10) :4033-4036
[6]   Antipneumococcal activity of LBM415, a new peptide diformylase inhibitor, compared with those of other agents [J].
Ednie, LM ;
Pankuch, G ;
Appelbaum, PC .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (10) :4027-4032
[7]   Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor [J].
Gross, M ;
Clements, J ;
Beckett, RP ;
Thomas, W ;
Taylor, S ;
Lofland, D ;
Ramanathan-Girish, S ;
Garcia, M ;
Difuntorum, S ;
Hoch, U ;
Chen, H ;
Johnson, KW .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (03) :487-493
[8]   Rapidly increasing prevalence of β-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae type b in patients with meningitis [J].
Hasegawa, K ;
Chiba, N ;
Kobayashi, R ;
Murayama, SY ;
Iwata, S ;
Sunakawa, K ;
Ubukata, M .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (05) :1509-1514
[9]   Antimicrobial spectrum and activity of NVP PDF-713, a novel peptide deformylase inhibitor, tested against 1,837 recent Gram-positive clinical isolates [J].
Jones, RN ;
Fritsche, TR ;
Sader, HS .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2004, 49 (01) :63-65
[10]   Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates [J].
Jones, RN ;
Moet, GJ ;
Sader, HS ;
Fritsche, TR .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (05) :804-807