Telomeres and telomerase: their mechanisms of action and the effects of altering their functions

被引:640
作者
Blackburn, EH [1 ]
机构
[1] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA
来源
FEBS LETTERS | 2005年 / 579卷 / 04期
关键词
telomere; telomerase;
D O I
10.1016/j.febslet.2004.11.036
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The molecular features of telomeres and telomerase are conserved among most eukaryotes. How telomerase and telomeres function and bow they interact to promote the chromosome-stabilizing properties of telomeres are discussed here. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:859 / 862
页数:4
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