Covalently supported porphyrins as ligands for the preparation of heme a3/CuB binuclear active site analogues of heme-copper terminal oxidases and metallation under mild conditions

被引：29

作者：

Baeg, JO ^{[1
]}

Holm, RH ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 05期

关键词：

D O I：

10.1039/a707785h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New covalently supported binucleating porphyrins have been prepared as potential structural and/or functional ligands for the iron-copper theme a(3)/Cu-B) active sites of heme-copper oxidases, and the introduction of iron and copper into one porphyrin under mild reaction conditions has been developed.

引用

页码：571 / 572

页数：2

共 25 条

[1] OXYGEN ACTIVATION AND THE CONSERVATION OF ENERGY IN CELL RESPIRATION
BABCOCK, GT
WIKSTROM, M
[J]. NATURE, 1992, 356 (6367) : 301 - 309
[2] CONGRUENT MULTIPLE MICHAEL ADDITION FOR THE SYNTHESIS OF BIOMIMETIC HEME ANALOGS
COLLMAN, JP
ZHANG, XM
HERRMANN, PC
UFFELMAN, ES
BOITREL, B
STRAUMANIS, A
BRAUMAN, JI
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (06) : 2681 - 2682
[3] A functional model related to cytochrome c oxidase and its electrocatalytic four-electron reduction of O-2
Collman, JP
Fu, L
Herrmann, PC
Zhang, XM
[J]. SCIENCE, 1997, 275 (5302) : 949 - 951
[4] Aza-crown-capped porphyrin models of myoglobin: Studies of the steric interactions of gas binding
Collman, JP
Herrmann, PC
Fu, L
Eberspacher, TA
Eubanks, M
Boitrel, B
Hayoz, P
Zhang, XM
Brauman, JI
Day, VW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (15) : 3481 - 3489
[5] A SYNTHETIC ANALOG FOR THE OXYGEN-BINDING SITE IN CYTOCHROME-C-OXIDASE
COLLMAN, JP
HERRMANN, PC
BOITREL, B
ZHANG, XM
EBERSPACHER, TA
FU, L
WANG, JL
ROUSSEAU, DL
WILLIAMS, ER
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (21) : 9783 - 9784
[6] Functional analogs of heme protein active sites
Collman, JP
[J]. INORGANIC CHEMISTRY, 1997, 36 (23) : 5145 - 5155
[7] PICKET-FENCE PORPHYRINS - SYNTHETIC MODELS FOR OXYGEN BINDING HEMOPROTEINS
COLLMAN, JP
GAGNE, RR
REED, CA
HALBERT, TR
LANG, G
ROBINSON, WT
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (06) : 1427 - 1439
[8] FAST REACTIONS OF CYTOCHROME-OXIDASE
EINARSDOTTIR, O
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1995, 1229 (02): : 129 - 147
[9] Heme/copper terminal oxidases
FergusonMiller, S
Babcock, GT
[J]. CHEMICAL REVIEWS, 1996, 96 (07) : 2889 - 2907
[10] Vibrational analysis of a molecular heme-copper assembly with a nearly linear Fe-III-CN-Cu-II bridge: Insight into cyanide binding to fully oxidized cytochrome c oxidase
Gardner, MT
Deinum, G
Kim, Y
Babcock, GT
Scott, MJ
Holm, RH
[J]. INORGANIC CHEMISTRY, 1996, 35 (23) : 6878 - 6884

← 1 2 3 →