Ancistroealaines A and B, two new bioactive naphthylisoquinolines, and related naphthoic acids from Ancistrocladus ealaensis

被引：94

作者：

Bringmann, G

Hamm, A

Günther, C

Michel, M

Brun, R

Mudogo, V

机构：

[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

[2] Schweizer Tropeninst, CH-4002 Basel, Switzerland

[3] Univ Kinshasa, Fac Sci, Kinshasa XI, DEM REP CONGO

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 11期

关键词：

D O I：

10.1021/np000247+

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new 5,8'-coupled naphthylisoquinoline alkaloids, ancistroealaines A (1) and B (2), eleutherolic acid (3), and two naphthoic acids, ancistronaphthoic acid A (4) and B (5), have been isolated from Ancistrocladus ealaensis. Their structures were determined by spectroscopic, chemical, and chiroptical methods. Ancistroealaine,A (1) exhibited activity against Leishmania donovani and Trypanosoma cruzi in vitro.

引用

页码：1465 / 1470

页数：6