Lipase-catalyzed polyester synthesis - A green polymer chemistry

被引:135
作者
Kobayashi, Shiro [1 ]
机构
[1] Kyoto Univ, Kyoto 6068501, Japan
来源
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES | 2010年 / 86卷 / 04期
关键词
polyester synthesis; lipase catalyst; lactone; ring-opening polymerization; condensation polymerization; green polymer chemistry; RING-OPENING POLYMERIZATION; ACID-DIVINYL ESTERS; ENZYMATIC-SYNTHESIS; DICARBOXYLIC-ACID; EPSILON-CAPROLACTONE; IMMOBILIZED LIPASE; ALIPHATIC POLYESTERS; ORGANIC MEDIA; LACTONES; COPOLYMERIZATION;
D O I
10.2183/pjab.86.338
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This article is a short comprehensive review describing in vitro polyester synthesis catalyzed by a hydrolysis enzyme of lipase, most of which has been developed for these two decades. Polyesters are prepared by repeated ester bond-formation reactions; they include two major modes, ring-opening polymerization (ROP) of cyclic monomers such as cyclic esters (lactones) and condensation polymerization via the reaction between a carboxylic acid or its ester group and an alcohol group. Polyester synthesis is, therefore, a reaction in reverse way of in vivo lipase catalysis of ester bond-cleavage with hydrolysis. The lipase-catalyzed polymerizations show very high chemo-, regio-, and enantio-selectivities and involve various advantageous characteristics. Lipase is robust and compatible with other chemical catalysts, which allows novel chemoenzymatic processes. New syntheses of a variety of functional polyesters and a plausible reaction mechanism of lipase catalysis are mentioned. The polymerization characteristics are of green nature currently demanded for sustainable society, and hence, desirable for conducting 'green polymer chemistry'.
引用
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页码:338 / 365
页数:28
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