Mechanisms of phenotypic heterogeneity in prion, Alzheimer and other conformational diseases

被引：6

作者：

Gambetti, Pierluigi ^{[1
]}

Parchi, Piero ^{[2
]}

Capellari, Sabina ^{[2
]}

Russo, Claudio ^{[3
]}

Tabaton, Massimo ^{[3
]}

Teller, Jan K. ^{[4
]}

Chen, Shu G. ^{[1
]}

机构：

[1] Case Western Reserve Univ, Inst Pathol, Cleveland, OH 44106 USA

[2] Univ Bologna, Inst Clin Neurol, I-40123 Bologna, Italy

[3] Univ Genoa, Inst Neurol, I-16132 Genoa, Italy

[4] East Carolina Univ, Dept Physiol, Greenville, NC 27858 USA

来源：

JOURNAL OF ALZHEIMERS DISEASE | 2001年 / 3卷 / 01期

关键词：

D O I：

10.3233/JAD-2001-3113

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

[No abstract available]

引用

页码：87 / 95

页数：9

共 52 条

[1] Unusual phenotypic alteration of β amyloid precursor protein (βAPP) maturation by a new Val-715→Met βAPP-770 mutation responsible for probable early-onset Alzheimer's disease [J].

Ancolio, K ;

Dumanchin, C ;

Barelli, H ;

Warter, JM ;

Brice, A ;

Campion, D ;

Frébourg, T ;

Checler, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) :4119-4124

[2] Polymorphism at codon 129 or codon 219 of PRNP and clinical heterogeneity in a previously unreported family with Gerstmann-Straussler-Scheinker disease (PrP-P102L mutation) [J].

Barbanti, P ;

Fabbrini, G ;

Salvatore, M ;

Petraroli, R ;

Cardone, F ;

Maras, B ;

Equestre, M ;

Macchi, G ;

Lenzi, GL ;

Pocchiari, M .

NEUROLOGY, 1996, 47 (03) :734-741

[3] CREUTZFELDT-JAKOB DISEASE PRION PROTEINS IN HUMAN BRAINS [J].

BOCKMAN, JM ;

KINGSBURY, DT ;

MCKINLEY, MP ;

BENDHEIM, PE ;

PRUSINER, SB .

NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (02) :73-78

[4]

BOLTON DC, 1984, BIOCHEMISTRY-US, V23, P5898, DOI 10.1021/bi00320a002

[5]

BORCHELT DR, 1992, J BIOL CHEM, V267, P16188

[6] Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo [J].

Borchelt, DR ;

Thinakaran, G ;

Eckman, CB ;

Lee, MK ;

Davenport, F ;

Ratovitsky, T ;

Prada, CM ;

Kim, G ;

Seekins, S ;

Yager, D ;

Slunt, HH ;

Wang, R ;

Seeger, M ;

Levey, AI ;

Gandy, SE ;

Copeland, NG ;

Jenkins, NA ;

Price, DL ;

Younkin, SG .

NEURON, 1996, 17 (05) :1005-1013

[7] AN ATAXIC FORM OF SUBACUTE PRESENILE POLIOENCEPHALOPATHY (CREUTZFELDT-JAKOB DISEASE) [J].

BROWNELL, B ;

OPPENHEIMER, DR .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1965, 28 (04) :350-+

[8] Conformational disease [J].

Carrell, RW ;

Lomas, DA .

LANCET, 1997, 350 (9071) :134-138

[9]

CAUGHEY B, 1991, J BIOL CHEM, V266, P18217

[10] PRION PROTEIN-BIOSYNTHESIS IN SCRAPIE-INFECTED AND UNINFECTED NEURO-BLASTOMA CELLS [J].

CAUGHEY, B ;

RACE, RE ;

ERNST, D ;

BUCHMEIER, MJ ;

CHESEBRO, B .

JOURNAL OF VIROLOGY, 1989, 63 (01) :175-181

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