Rabies virus receptors

被引：230

作者：

Lafon, M ^{[1
]}

机构：

[1] Inst Pasteur, Dept Neurosci, Unite Neuroimmunol Virale, F-75724 Paris 15, France

来源：

JOURNAL OF NEUROVIROLOGY | 2005年 / 11卷 / 01期

关键词：

nAChR; NCAM; p75NTR; rabies virus;

D O I：

10.1080/13550280590900427

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells. Other components of the cell membrane, such as gangliosides, may also participate in the entry of rabies virus. However, little is known of the role of these molecules in vivo. This review proposes a speculative model that accounts for the role of these different molecules in entry and trafficking of rabies virus into the nervous system.

引用

页码：82 / 87

页数：6

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