Nature or nurture in mosquito resistance to malaria?

被引：4

作者：

Hurd, Hilary ^{[1
]}

机构：

[1] Univ Keele, Inst Sci & Technol Med, Ctr Appl Entomol & Parasitol, Keele ST5 5BG, Staffs, England

来源：

TRENDS IN PARASITOLOGY | 2007年 / 23卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/j.pt.2007.01.011

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The genetic basis of mosquito resistance to malaria parasites is well established and currently receives a lot of attention. However this is not the sole determinant of the success or failure of an infection. In a recent article, Lambrechts and colleagues report the influence of the quality of the external environment of a mosquito on infection. They indicate that external variations could substantially reduce the importance of resistance genes in determining infection by malaria parasites. Furthermore, these variations could influence future plans to use malaria-resistant transgenic mosquitoes to control parasite transmission.

引用

收藏

页码：135 / 138

页数：4

相关论文

共 18 条

[11] Effect of adult nutrition on the melanization immune response of the malaria vector Anopheles stephensi [J].

Koella, JC ;

Sorensen, FL .

MEDICAL AND VETERINARY ENTOMOLOGY, 2002, 16 (03) :316-320

[12] Environmental influence on the genetic basis of mosquito resistance to malaria parasites [J].

Lambrechts, Louis ;

Chavatte, Jean-Marc ;

Snounou, Georges ;

Koella, Jacob C. .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2006, 273 (1593) :1501-1506

[13] HETEROGENEITY IN PATTERNS OF MALARIAL OOCYST INFECTIONS IN THE MOSQUITO VECTOR [J].

MEDLEY, GF ;

SINDEN, RE ;

FLECK, S ;

BILLINGSLEY, PF ;

TIRAWANCHAI, N ;

RODRIGUEZ, MH .

PARASITOLOGY, 1993, 106 :441-449

[14] Mosquito immunity against Plasmodium [J].

Michel, K ;

Kafatos, FC .

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2005, 35 (07) :677-689

[15] Microsatellite DNA polymorphism and heterozygosity among field and laboratory populations of Anopheles gambiae s.s. (Diptera: Culicidae) [J].

Norris, DE ;

Shurtleff, AC ;

Touré, YT ;

Lanzaro, GC .

JOURNAL OF MEDICAL ENTOMOLOGY, 2001, 38 (02) :336-340

[16] Melanization of Plasmodium falciparum and c-25 sephadex beads by field-caught Anopheles gambiae (Diptera: Culicidae) from southern Tanzania [J].

Schwartz, A ;

Koella, JC .

JOURNAL OF MEDICAL ENTOMOLOGY, 2002, 39 (01) :84-88

[17] REINTERPRETATION OF THE GENETICS OF SUSCEPTIBILITY OF AEDES-AEGYPTI TO PLASMODIUM-GALLINACEUM [J].

THATHY, V ;

SEVERSON, DW ;

CHRISTENSEN, BM .

JOURNAL OF PARASITOLOGY, 1994, 80 (05) :705-712

[18] Thermal biology in insect-parasite interactions [J].

Thomas, MB ;

Blanford, S .

TRENDS IN ECOLOGY & EVOLUTION, 2003, 18 (07) :344-350