Enhancing the enantioselectivity of lipase in transesterification by substrate matching: An enzyme memory based approach

被引：28

作者：

Lee, D ^{[1
]}

Choi, YK ^{[1
]}

Kim, MJ ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol, Dept Chem, Div Mol & Life Sci, Pohang 790784, Kyungbuk, South Korea

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 16期

关键词：

D O I：

10.1021/ol0062897

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The substrate matching strategy is described as a new approach for effectively enhancing the lipase enantioselectivity in organic solvent. In the lipase-catalyzed transesterifications of 3a-c, higher enantioselectivities have been achieved using 1a-c, respectively, as the structurally matched acyl donors.

引用

页码：2553 / 2555

页数：3

共 33 条

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