Micacocidin A, B and C, novel antimycoplasma agents from Pseudomonas sp. -: II.: Structure elucidation

被引：45

作者：

Kobayashi, S

Nakai, H

Ikenishi, Y

Sun, WY

Ozaki, M

Hayase, Y ^{[1
]}

Takeda, R

机构：

[1] Shionogi & Co Ltd, Aburahi Labs, Shiga 5203423, Japan

[2] Shionogi & Co Ltd, Shionogi Res Labs, Fukushima Ku, Osaka 5530002, Japan

来源：

JOURNAL OF ANTIBIOTICS | 1998年 / 51卷 / 03期

关键词：

D O I：

10.7164/antibiotics.51.328

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Metal-containing novel heterocyclic antibiotics, micacocidin A (1), B (2), and C (3) have been isolated from the culture filtrate of Pseudomonas sp. No. 57-250. The structure and absolute configuration of micacocidin A, an octahedral Zn2+ complex, was determined by X-ray crystallographic analysis. And then, the structures of the two congeners, micacocidin B (Cu2+ complex) and C (Fe3+ complex) were investigated by employing one dimensional and two dimensional homonuclear and heteronuclear NMR spectroscopies and mass spectrometry.

引用

页码：328 / 332

页数：5

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