Micacocidin A, B and C, novel antimycoplasma agents from Pseudomonassp. -: I.: Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

被引：40

作者：

Kobayashi, S ^{[1
]}

Hidaka, S ^{[1
]}

Kawamura, H ^{[1
]}

Ozaki, M ^{[1
]}

Hayase, Y ^{[1
]}

机构：

[1] Shionogi & Co Ltd, Aburahi Labs, Shiga 5203423, Japan

来源：

JOURNAL OF ANTIBIOTICS | 1998年 / 51卷 / 03期

关键词：

D O I：

10.7164/antibiotics.51.323

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A Gram-negative bacterium was found to produce a new zinc-containing antibiotics, micacocidin A and related compounds containing Cu or Fe, micacocidin B and C, respectively. These antibiotics were isolated by column chromatography on silica gel, and then separated by preparative TLC and HPLC. These new antibiotics exhibited an excellent activity against Mycoplasma species. The producing bacterium was characterized and ascribed to the genus Pseudomonas.

引用

页码：323 / 327

页数：5

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