Impaired detrusor contractility in community-dwelling elderly presenting with lower urinary tract symptoms

被引:127
作者
Abarbanel, Joseph
Marcus, Esther-Lee
机构
[1] Hasharon Hosp, Rabin Med Ctr, Dept Urol, IL-49372 Petah Tiqwa, Israel
[2] Herzog Hosp, Dept Acute Geriatr, Jerusalem, Israel
关键词
D O I
10.1016/j.urology.2006.11.019
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES To determine the prevalence of impaired detrusor contractility (IDC) with and without detrusor hyperactivity (DH) among community-dwelling elderly with lower urinary tract symptoms and to identify which patients are at a greater risk of having a hypocontractile detrusor. METHODS We performed a retrospective chart review of all patients 70 years old or older with storage and/or voiding lower urinary tract symptoms who had undergone urodynamic pressure-flow studies in a urodynamic referral center during a 2-year period. RESULTS During the study period, 181 patients (82 men [45%] and 99 women [55%]), aged 70 years or older (mean age 75.7 +/- 4.8), underwent urodynamic studies. IDC was detected in 39 (48%) of the 82 men and in 12 (12%) of the 99 women. Two thirds of the men and one half of the women with IDC also had involuntary detrusor contractions during the filling phase and/or low bladder compliance. The prevalence of IDC/DH-IDC was significantly greater in those with a history of urinary retention and an indwelling urethral catheter. CONCLUSIONS Detrusor-impaired contractility is an important pathophysiologic mechanism in older patients with lower urinary tract symptoms, especially in men. Establishing the diagnosis by urodynamic pressure-flow studies is crucial for determining treatment-potentially harmful to this vulnerable population-from objective parameters rather than by empirical decisions.
引用
收藏
页码:436 / 440
页数:5
相关论文
共 26 条
[11]  
GIFFITHS DJ, 1986, AM J PHYSIOL, V251, pR225
[12]   Effect of bladder outlet obstruction on detrusor smooth muscle cell:: An in vitro study [J].
Gong, Y ;
Song, B ;
Jin, XY ;
Xiong, EQ .
JOURNAL OF SURGICAL RESEARCH, 2003, 114 (02) :202-209
[13]  
GRIFFITHS DJ, 2004, J UROL NEPHROL S, V215, P93
[14]   Prevalence and characteristics of voiding difficulties in women: Are subjective symptoms substantiated by objective urodynamic data? [J].
Groutz, A ;
Gordon, D ;
Lessing, JB ;
Wolman, I ;
Jaffa, A ;
David, MP .
UROLOGY, 1999, 54 (02) :268-272
[15]   URODYNAMIC FINDINGS IN PATIENTS WITH DIABETIC CYSTOPATHY [J].
KAPLAN, SA ;
TE, AE ;
BLAIVAS, JG .
JOURNAL OF UROLOGY, 1995, 153 (02) :342-344
[16]   Analysis of the pathophysiology of lower urinary tract symptoms in patients after prostatectomy [J].
Kuo, HC .
UROLOGIA INTERNATIONALIS, 2002, 68 (02) :99-104
[17]   The role of urodynamics in the evaluation of voiding dysfunction in men after cerebrovascular accident [J].
Nitti, VW ;
Adler, H ;
Combs, AJ .
JOURNAL OF UROLOGY, 1996, 155 (01) :263-266
[18]   The aging bladder - a significant but underestimated role in the development of lower urinary tract symptoms [J].
Nordling, J .
EXPERIMENTAL GERONTOLOGY, 2002, 37 (8-9) :991-999
[19]  
Resnick NM, 1996, NEUROUROL URODYNAM, V15, P599, DOI 10.1002/(SICI)1520-6777(1996)15:6<599::AID-NAU2>3.0.CO
[20]  
2-A